Biotechnology

Microenvironment and tumor exosomes are allies in the metastatic process

Microenvironment and tumor exosomes are allies in the metastatic process

Dr. Héctor Peinado Head of the Microenvironment and Metastasis Group Spanish Oncologic Research Center (CNIO)


July 11, 2016 | Applied Genomics

Alterations to Natural Immunity: Complement Genes and Predisposition to Disease

Alterations to Natural Immunity: Complement Genes and Predisposition to Disease

Santiago Rodríguez de Córdoba, Biological Research Centre (CSIC) and the Rare Disease Biomedical Research Networking Centre (CIBERER). Madrid, Spain


Until not long ago, diseases related to the complement system were almost exclusively limited to the lack of one its components, and were fundamentally associated with a predisposition to infections, immune complex diseases, or autoimmune diseases. During the last 15 years, a number of whole genome linkage analyses and whole genome association studies have revealed that the association between the complement and disease is far more important and complex than we had thought previously.
June 21, 2016 | Applied Genomics

Bottom-up Synthetic Biology: Reconstitution and Engineering of Functional Macromolecular Devices

Bottom-up Synthetic Biology: Reconstitution and Engineering of Functional Macromolecular Devices

Rafael Giraldo y Germán Rivas Department of Cell and Molecular Biology Center of Biological Research - CSIC


April 14, 2016 | New Pathways

Intersections with Mario Bunge in the interdisciplinary space of the matter and mind interrelation: a new case of intellectual evolutionary convergence

Intersections with Mario Bunge in the interdisciplinary space of the matter and mind interrelation: a new case of intellectual evolutionary convergence

Emilio Muñoz. Institute of Philosophy, CSIC and Unit of Research in Scientific Culture, CIEMAT


An introductory reflection

Once more, I will deal with the subject of intellectual evolutionary convergence. This time, however, under a new perspective, focused on strategy and results-oriented aspects.

March 01, 2016 | Editorial

Intellectual Evolutionary Convergence: Unexpected endorsements for the synthesis on evolution and the sociability environment.

Intellectual Evolutionary Convergence: Unexpected endorsements for the synthesis on evolution and the sociability environment.


In May of 2015, I published in this platform an article offering a synthesis of the theory of evolution. In it, I formulated a new concept: NACE (NAture, Culture, Ethics), or the “sociability environment”, that I claimed plays a key role in the evolution processes. With that publication, I intended to put an end to years of research investigating the relationship between biology and economics, within the theoretical framework of evolution; a research that I felt compelled to do by the effects of the global economic and socio-political crisis that began in 2007-2008. 

January 11, 2016 | Editorial

Systemic Reflections on the Spanish Health Biotech Business Sector

Systemic Reflections on the Spanish Health Biotech Business Sector

César Ullastres. Independent Professional.


The biotech firms in the field of human healthcare are many of the most representative members of the Spanish System of Science, Technology and Innovation (SSSTI). Looking at it in a different way - and putting the focus on the relationship between the different actors forming the SSSTI - may open up new, easier paths.
September 21, 2015 | New Pathways

Stem Cell Therapies for Parkinson´s Disease

Stem Cell Therapies for Parkinson´s Disease

Isabel Fariñas. Department of Cell Biology at the University of Valencia. Center for Networked Biomedical Research (CIBER) in Neurodegenerative Diseases


The increased incidence of neurodegenerative diseases poises an important social problem. The ideal way to fight these diseases, with all of them being characterized by abnormal protein accumulation and progressive neuronal loss, would be to discover their causes and associated biomarkers with which to detect them in their early stages. Unfortunately, these diseases can only be diagnosed in their advanced stages, when large numbers of neurons have been lost. This is why neuron restoration through transplantation is regarded as a reasonable therapeutic approach. 

August 28, 2015 | New Pathways

Advances in Gene Therapies: Recent outcomes in hereditary hematologic diseases

Advances in Gene Therapies: Recent outcomes in hereditary hematologic diseases

Juan A. Bueren. Division of Innovative Therapies. CIEMAT and CIBER of Rare Diseases. Mixed Unit for Advanced Therapies. IIS Fundación Jiménez Díaz (UAM)/CIEMAT.


The development of new gene transfer vectors has allowed scientists to launch a new generation of gene therapy clinical trials, whose efficacy and safety will unquestionably bring a substantial change in the way we treat certain diseases with poor prognosis.
July 20, 2015 | New Pathways

A synthesis of the evolution theory: survival, adaptation and environment for sociability

A synthesis of the evolution theory: survival, adaptation and environment for sociability

Emilio Muñoz. Institute of Philosophy, Centre for Human and Social Sciences (CCHS), Spanish National Research Council (CSIC), Scientific Culture Research Unit, CIEMAT.


It is my intention to offer here a synthetic, integrated vision of the theory of evolution after having spent eight years reflecting upon the relationship between diverse subject matters and areas such as biology, economics and politics.

The spark leading to this process has been the systemic economic global crisis, whose solution has involved, in the opinion of this author, excessively dogmatic solutions that ignored the importance of the historical and cultural backgrounds and set aside scientific research, and especially the application of the scientific method. 
May 19, 2015 | Editorial

Current limitations to the implementation of personalized medicine in Spanish hospitals

Current limitations to the implementation of personalized medicine in Spanish hospitals

Adolfo López de Munain is a neurologist at the Donostia Hospital and head of the neurosciences area of the Biodonostia Institute for Biomedical Research at San Sebastian


Upon the publication of the preliminary results of the Human Genome Project in 2003, a wave of optimism swept the laboratories of biomedical research, leading us all, clinicians and patients alike, to believe that within a short period of time we could have the answer for all the ills of genetic origin.
April 17, 2015 | Applied Genomics

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